BEA core facility

Platforms

The microarray platforms at BEA and their applications can be found in the table below.

A more detailed description of each platform will follow, including the ABI qRT-PCR and Agilent Bioanalyzer system.

Affymetrix GeneChip System for Array Cartridges A pioneer in genetic analysis, Affymetrix introduced highly parallel genetic assays to the marketplace by commercializing the first DNA microarray in the late 1980s. Today researchers around the world use Affymetrix technologies to better understand the role that genes play in disease, the effectiveness and safety of therapies, and many other biological factors that affect human well-being. Applications include SNP and CNV genotyping, expression analysis and epigenetics. GeneChip System Affymetrix webpage
Affymetrix GeneTitan System for Array Plates The GeneTitan family of instruments and proven GeneChip Array Plates from Affymetrix are the first to provide a hands-free, automated solution for monitoring gene expression and genome-wide SNP genotyping. The GeneTitan Instrument and the GeneTitan Multi-Channel (MC) Instrument automate array processing from target hybridization to data generation by combining a hybridization oven, fluidics processing, and state-of-the art imaging device into a single bench-top instrument. GeneTitan system Affymetrix webpage
Agilent Microarray Platform Agilent is advancing the art of manufacturing microarrays with SurePrint, a powerful combination of probe design algorithms and validation methods, maskless & highly-flexible microarray printing based on industrial-scale inkjet technologies, and unique QC processes. The result is affordable, accessible pre-printed microarrays that content researchers can trust. Find out more about the powerful SurePrint, SureScan, and SureHyb technologies behind Agilent's microarray platform. Agilent microaray system Agilent webpage
Illumina iScan System The iScan System is a cutting-edge, dedicated array scanner that supports rapid, sensitive, and accurate imaging of Illumina's array-based genetic analysis products. The system features a high signal-to-noise ratio, high sensitivity, an excellent limit of detection, and a broad dynamic range leading to exceptionally high data quality. Illumina iScan system Illumina webpage
Applied Biosystems 7900HT Real-Time PCR System This system combines thermal cycling, fluorescence detection, and application-specific software to provide an integrated platform for the detection and quantification of nucleic acid sequences. Real-time PCR reactions run using 96-well plates, 384-well plates and TILDA cards and can be completed in under two hours. ABI 7900HT Real-Time PCR System ABI wepage
Agilent 2100 Bioanalyzer Platform Agilents Bioanalyzer uses microfluidic Lab-on-a-chip technology for the analysis of DNA, RNA and proteins as an alternative to standard gel electrophoresis techniques. It offers fast, reproducible and high quality digital data with minimal sample and reagent consumption. Importantly, it facilitates the analysis of total RNA integrity for gene expression analysis by automatically calculating the ratio of ribosomal bands in total RNA samples. ABI 7900HT Real-Time PCR System Agilent webpage